REGLAN Injection (metoclopramide injection, USP)
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Normal and reverse flow injection–spectrophotometric determination of thiamine hydrochloride in pharmaceutical preparations using diazotized metoclopramide
Simple and sensitive normal and reverse flow injection methods for spectrophotometric determination of thiamine hydrochloride (THC) at the microgram level were proposed and optimized. Both methods are based on the reaction between THC and diazotized metoclopramide in alkaline medium. Beer's law was obeyed over the range of 10-300 and 2-90 μg/mL, the limits of detection were 2.118 and 0.839 μg/m...
متن کاملThe effects of remifentanil, lidocaine, metoclopramide, or ketamine pretreatment on propofol injection pain.
BACKGROUND Propofol injection pain is a frequent and a well-known complaint distressing for the patients. Although the ethiology of this pain remains obscure, the ideal method for the prevention of propofol injection pain is still controversial. Local anesthetics, opioids, nonsteroidal anti-inflammatory drugs, ketamine, metoclopramide, droperidol have been tested. We aimed to conduct a study co...
متن کاملRole of dopamine in the regulation of blood pressure and the renin--angiotensin--aldosterone system in conscious rats.
1. In conscious rats, intracerebroventricular injection of dopamine resulted in a decrease in blood pressure, whereas injection of metoclopramide, the dopamine antagonist, produced an increase in blood pressure. The central depressor effect of dopamine was attenuated by a subpressor pretreatment with intraventricular metoclopramide, but not by phentolamine. 2. Intravenous administration of dopa...
متن کاملMetoclopramide-induced central nervous system depression in the chicken
BACKGROUND Metoclopramide is a dopamine D2-receptor antagonist used as an antiemetic and gastroprokinetic agent in man and animals. The drug causes sedation as a side effect in man. Such a sedative action of metoclopramide has not been documented in the chicken as the drug is not used clinically in this species. The present study examines the central nervous system depressant effects of metoclo...
متن کاملFlow-injection chemiluminescent determination of metoclopramide hydrochloride in pharmaceutical formulations and biological fluids using the [Ru(dipy)(3)(2+)]-permanganate system.
A flow-injection (FI) methodology using (2,2'-dipyridyl) ruthenium(II) [Ru(dipy)(3)(2+)] chemiluminescence (CL) was developed for the rapid and sensitive determination of metoclopramide hydrochloride. The method is based on the CL reaction of metoclopramide with Ru(dipy)(3)(2+) and KMnO(4) in a sulfuric acid medium. Under the optimum conditions, a calibration graph was obtained over the concent...
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